CapC, a Novel Autotransporter and Virulence Factor of Campylobacter jejuni
نویسندگان
چکیده
منابع مشابه
A Molecular Survey of Campylobacter jejuni and Campylobacter Coli Virulence and Diversity
Background: The aim of this study was to determine the prevalence of virulence-associated genes and enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) analysis of Campylobacter spp. isolated from children with diarrhea in Iran. Methods: A total of 200 stool specimens were obtained from children under 5 years during July 2012 to July 2013. Detection of C. jejuni and C. coli was perfo...
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Campylobacter jejuni is the major cause of human bacterial diarrhea worldwide. Its pathogenic mechanism remains poorly understood. cj0371 is a novel gene that was uncovered using immunoscreening. There have been no previous reports regarding its function. In this study, we constructed an insertion mutant and complement of this gene in C. jejuni and examined changes in virulence. We observed tha...
متن کاملa molecular survey of campylobacter jejuni and campylobacter coli virulence and diversity
background: the aim of this study was to determine the prevalence of virulence-associated genes and enterobacterial repetitive intergenic consensus pcr (eric-pcr) analysis of campylobacter spp. isolated from children with diarrhea in iran. methods: a total of 200 stool specimens were obtained from children under 5 years during july 2012 to july 2013. detection of c. jejuni and c. coli was perfo...
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Campylobacter jejuni bacteria are highly diverse enteropathogens. Seventy-three C. jejuni isolates from blood collected in Finland were analyzed by multilocus sequence typing and serum resistance. Approximately half of the isolates belonged to the otherwise uncommon sequence type 677 clonal complex. Isolates of this clonal complex were more resistant than other isolates to human serum.
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Thermotolerant Campylobacter spp. frequently cause bacterial gastroenteritis in humans commonly infected through the consumption of undercooked poultry meat. We examined Campylobacter jejuni heat-stress responses in vitro after exposure to 48°C and 55°C. The in vivo modulation of its pathogenicity was also investigated using BALB/c mice intravenously infected with stressed C. jejuni. Regardless...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 2018
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.01032-18